by
Zeynep Kalaycıoğlu | Ara 05, 2024
Kahveci and coworkers have developed two groundbreaking materials with significant potential in biomedical applications.
Kahveci and coworkers have developed two groundbreaking materials with significant potential in biomedical applications.
The first innovation involves chitosan-based nanofibers incorporating the antioxidant gallic acid (GA), fabricated through electrospinning and cross-linked with glutaraldehyde. These poly(vinyl alcohol)/chitosan nanofibers (PVA-CS-GAs) demonstrated promising properties for wound healing and drug delivery. Scanning electron microscopy (SEM) revealed nanofiber diameters ranging between 90–110 nm. Antioxidant tests showed strong radical scavenging ability, while in vitro studies confirmed pH-dependent drug release rates, highlighting their suitability for advanced healthcare uses. (https://doi.org/10.1016/j.ijbiomac.2024.136055)
In the second study, scientists synthesized graphene-encapsulated iron nanoparticles using solvothermal and chemical vapor deposition (CVD) methods. The nanoparticles were surface-modified with pyrene-functionalized POEGMA via atom transfer radical polymerization (ATRP). Cytotoxicity tests on MCF-7 cancer cell lines showed that these magnetic nanoparticles are cytocompatible at concentrations below 500 μg/mL, with potential for drug delivery due to their small size, stability, and biocompatibility. (https://doi.org/10.1016/j.jsamd.2024.100776)
These breakthroughs could revolutionize drug delivery and wound healing technologies, paving the way for next-generation biomedical solutions.
